Gene

ND-42

Species
Drosophila melanogaster
Symbol
ND-42
Name
NADH dehydrogenase (ubiquinone) 42 kDa subunit
Synonyms
  • A10
  • CG6343
Biotype
protein coding gene
Automated Description
Predicted to be involved in mitochondrial electron transport, NADH to ubiquinone. Located in mitochondrion. Part of respiratory chain complex I. Is expressed in several structures, including adult head; adult heart; embryonic/larval midgut primordium; gut section; and larval muscle cell. Used to study Leigh disease. Human ortholog(s) of this gene implicated in nuclear type mitochondrial complex I deficiency 22. Orthologous to human NDUFA10 (NADH:ubiquinone oxidoreductase subunit A10).
FB Description
NADH dehydrogenase (ubiquinone) 42 kDa subunit (ND-42) encodes an ortholog of human NDUFA10, a subunit of complex I of the mitochondrial electron transport chain (NADH:ubiquinone reductase). ND-42 acts genetically as a suppressor of some Pink1 phenotypes.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR10513
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R6
Viewer Help
22.0278M22.0280M22.0282M22.0284M22.0286M22.0288M22.0290M22.0292M

Sequence Details

Loading...

Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions