Version: 8.0.0
Date: Tue Jan 28 2025
GluRIIB
Drosophila melanogasterFB:FBgn0020429
SummaryOrthologyParalogyFunction - GO AnnotationsPathwaysPhenotypesDisease AssociationsAlleles and VariantsTransgenic AllelesModelsSequence Feature ViewerSequence DetailsExpressionMolecular InteractionsGenetic Interactions
Gene

GluRIIB

Species
Drosophila melanogaster
Symbol
GluRIIB
Name
Glutamate receptor IIB
Synonyms
  • CG7234
  • DGluIIB
Biotype
protein coding gene
Automated Description
Enables glutamate-gated calcium ion channel activity. Involved in calcium ion transport; glutamatergic synaptic transmission; and neuromuscular synaptic transmission. Located in muscle cell postsynaptic specialization and postsynaptic membrane. Part of ionotropic glutamate receptor complex. Is expressed in embryonic/larval hypodermal muscle cell; embryonic/larval neuromuscular junction; larval somatic muscle cell; larval visceral muscle cell; and somatic muscle cell. Orthologous to human GRIK4 (glutamate ionotropic receptor kainate type subunit 4).
FB Description
Glutamate receptor IIB (GluRIIB) encodes a subunit of the muscle glutamate receptor that responds to neurotransmitter at the neuromuscular junction.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR18966
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
Phenotype Term
Annotation details
References
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    Disease Associations

    Cases where the expected disease association was NOT found
    Cell color indicative of annotation volume
    No data available

    Alleles and Variants

    Allele/Variant Symbol
    Allele Synonyms
    Category
    Variant
    Variant type
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      Transgenic Alleles

      Species
      (carrying the transgene)
      Allele symbol
      Transgenic construct
      Expressed components
      Knock-down targets
      Regulatory regions
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        Models

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        Associated Human Diseases
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          Sequence Feature Viewer

          Genome location
          Assembly version
          R6
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          Data currently unavailable; sequence viewer under construction

          Sequence Details

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          Expression

          Primary Sources
          Other Sources
          Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

          Molecular Interactions

          GluRIIB molecule type
          Interactor gene
          Interactor species
          Interactor molecule type
          Detection methods
          Source
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            Genetic Interactions

            GluRIIB role
            GluRIIB genetic perturbation
            Interactor gene
            Interactor species
            Interactor role
            Interactor genetic perturbation
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            Phenotype or trait
            Source
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