Gene

Actβ

Species
Drosophila melanogaster
Symbol
Actβ
Name
Activin-beta
Synonyms
  • Act
  • act
Biotype
protein coding gene
Automated Description
Predicted to enable cytokine activity. Involved in several processes, including nervous system development; positive regulation of imaginal disc growth; and positive regulation of neuroblast proliferation. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in several structures, including epithelial cell; ganglia; inner photoreceptor cell; male germline cell; and presumptive embryonic/larval system. Orthologous to several human genes including INHBA (inhibin subunit beta A); INHBB (inhibin subunit beta B); and INHBC (inhibin subunit beta C).
FB Description
Activin-beta (Actbeta) encodes a ligand of the TGF beta superfamily. It signals through the type I receptor encoded by babo and the Smad family member encoded by Smox. Actbeta is expressed primarily in the central and peripheral nervous systems and its product regulates aspects of metabolism, insulin signaling, hemocyte development and body size.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR11848
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R6
Viewer Help
1.078M1.079M1.080M1.081M1.082M1.083M1.084M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions