Predicted to enable cytokine activity. Involved in several processes, including nervous system development; positive regulation of imaginal disc growth; and positive regulation of neuroblast proliferation. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in several structures, including epithelial cell; ganglia; inner photoreceptor cell; male germline cell; and presumptive embryonic/larval system. Orthologous to several human genes including INHBA (inhibin subunit beta A); INHBB (inhibin subunit beta B); and INHBC (inhibin subunit beta C).
FB Description
Activin-beta (Actbeta) encodes a ligand of the TGF beta superfamily. It signals through the type I receptor encoded by babo and the Smad family member encoded by Smox. Actbeta is expressed primarily in the central and peripheral nervous systems and its product regulates aspects of metabolism, insulin signaling, hemocyte development and body size.