Gene

gus

Species
Drosophila melanogaster
Symbol
gus
Name
gustavus
Synonyms
  • A11
  • CG2944
Biotype
protein coding gene
Automated Description
Involved in several processes, including dorsal appendage formation; germ cell migration; and regionalization. Located in several cellular components, including cell cortex; perinuclear region of cytoplasm; and pole plasm. Part of Cul5-RING ubiquitin ligase complex and elongin complex. Is expressed in germarium; nurse cell; oocyte; organism; and ovary. Orthologous to human SPSB1 (splA/ryanodine receptor domain and SOCS box containing 1) and SPSB4 (splA/ryanodine receptor domain and SOCS box containing 4).
FB Description
gustavus (gus) encodes a cullin-RING ubiquitin E3 ligase specificity receptor. It interacts genetically and physically with the product of Cul5, and putatively regulates stability of target proteins including the one encoded by vas. It is involved in oogenesis and germ cell maintenance.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR12245
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R6
Viewer Help
5.118M5.120M5.122M5.124M5.126M5.128M

Sequence Details

Loading...

Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions