Version: 8.0.0
Date: Tue Jan 28 2025
Tgt
Drosophila melanogasterFB:FBgn0031321
SummaryOrthologyParalogyFunction - GO AnnotationsPathwaysPhenotypesDisease AssociationsAlleles and VariantsTransgenic AllelesModelsSequence Feature ViewerSequence DetailsExpressionMolecular InteractionsGenetic Interactions
Gene

Tgt

Species
Drosophila melanogaster
Symbol
Tgt
Name
tRNA-guanine transglycosylase
Synonyms
  • CG4947
  • tgt
Biotype
protein coding gene
Automated Description
Predicted to enable tRNA-guanosine(34) queuine transglycosylase activity. Predicted to be involved in tRNA-guanine transglycosylation. Predicted to be located in cytoplasmic side of mitochondrial outer membrane. Predicted to be part of tRNA-guanine transglycosylase complex. Is expressed in organism. Orthologous to human QTRT1 (queuine tRNA-ribosyltransferase catalytic subunit 1).
FB Description
Not Available
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR43530
Stringency:
Additional filters to further constrain the results:
Species Gene symbol Count Best Best reverse
Method
Ensembl ComparaHGNCHieranoidInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidXenbaseZFIN
Homo sapiensQTRT19 of 9YesYes☑ ☑☑☑☑☑☑☑☑  
Mus musculusQtrt19 of 9YesYes☑ ☑☑☑☑☑☑☑☑  
Rattus norvegicusQtrt18 of 9YesYes☐ ☑☑☑☑☑☑☑☑  
Xenopus tropicalisqtrt19 of 9YesYes☑ ☑☑☑☑☑☑☑☑  
Danio rerioqtrt19 of 10YesYes☑ ☑☑☑☑☑☑☑☑ ☐
Caenorhabditis eleganstgt-18 of 9YesYes☐ ☑☑☑☑☑☑☑☑  
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Gene symbolRank Alignment Length (aa) Similarity %Identity %Method Count
Method
Ensembl ComparaHGNCInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidSGD
CG3434140540242 of 8☑ ☐☐☐☐☐☑☐ 

Function - GO Annotations

No function available for that gene

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
No data available

Disease Associations

Cases where the expected disease association was NOT found
all annotationsall disease by infectious agentbacterial infectious diseasefungal infectious diseaseparasitic infectious diseaseviral infectious diseaseall disease of anatomical entitycardiovascular system diseasecentral nervous system diseaseendocrine system diseasegastrointestinal system diseasehematopoietic system diseaseimmune system diseaseintegumentary system diseasemusculoskeletal system diseaseperipheral nervous system diseasereproductive system diseaserespiratory system diseasesensory system diseasethoracic diseaseurinary system diseaseall disease of cellular proliferationbenign neoplasmcancerpre-malignant neoplasmall genetic diseasechromosomal diseasemonogenic diseasepolygenic diseaseall other diseasedisease of mental healthdisease of metabolismphysical disordersyndrome
Tgt (Dme)
Cell color indicative of annotation volume
No data available

Alleles and Variants

Genome location
Assembly version
R6
Viewer Help
1.1842M1.1844M1.1846M1.1848M1.1850M1.1852M1.1854M1.1856M
Variant Types and ConsequencesOnly variants associated to alleles are shown in the graphics above. See all variants in JBrowse.
Allele/Variant Symbol
Allele Synonyms
Category
Variant
Variant type
Molecular consequence
Has Disease Annotations
Has Phenotype Annotations
TgtSK8
  • CG4947[SK8]
  • CG4947SK8
allele with one associated variant
deletion
  • frameshift variant
TgtSK1
  • CG4947[SK1]
  • CG4947SK1
allele with one associated variant
deletion
  • frameshift variant
NT_033779.5:g.1184083T>Cvariant
SNP
  • 5 prime UTR variant
NT_033779.5:g.1185325G>Cvariant
SNP
  • missense variant
NT_033779.5:g.1184136A>Gvariant
SNP
  • 5 prime UTR variant
NT_033779.5:g.1184272G>Avariant
SNP
  • intron variant
NT_033779.5:g.1184407G>Tvariant
SNP
  • missense variant
NT_033779.5:g.1185680A>Cvariant
SNP
  • 3 prime UTR variant
NT_033779.5:g.1184273A>Tvariant
SNP
  • intron variant
NT_033779.5:g.1184710A>Cvariant
SNP
  • synonymous variant
Showing 1 - 10 of 87 rows
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View detailed Alleles/Variants information
Download all Alleles/Variants for all genes of the species

Transgenic Alleles

Species
(carrying the transgene)
Allele symbol
Transgenic construct
Expressed components
Knock-down targets
Regulatory regions
Has Disease Annotations
Has Phenotype Annotations
Drosophila melanogasterTgtGD11482
P{GD11482}
  • UASt
Drosophila melanogasterTgtKK109107
P{KK109107}
  • UASt
Drosophila melanogasterTgtU6.NIG.sgRNA
P{U6-Tgt.NIG.sgRNA}
Showing 1 - 3 of 3 rows
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Models

No data available

Sequence Feature Viewer

Genome location
Assembly version
R6
Viewer Help
1.1842M1.1844M1.1846M1.1848M1.1850M1.1852M1.1854M1.1856M

Sequence Details

Loading...

Expression

Primary Sources
Other Sources
all annotationsall anatomical structuresalimentary part of gastrointestinal systemchemosensory systemcirculatory systemendocrine systemexocrine systemhemolymphoid systemhepatobiliary systemintegumental systemmechanosensory systemmusculoskeletal systemnervous systemrenal systemreproductive systemrespiratory systemsensory systemvestibulo-auditory systemvisual systemendodermectodermmesodermmesenchymeadipose tissueappendageentire extraembryonic componentimaginal precursorpharyngeal archotherall stagesembryo stagepost embryonic, pre-adultpost-juvenile adult stageall cellular componentsextracellular regionplasma membranesynapsecell junctioncell projectioncytoplasmic vesicleendosomevacuolegolgi apparatusendoplasmic reticulumcytosolmitochondrionnucleuschromosomecytoskeletonprotein-containing complexother locations
Tgt (Dme)
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

5 interactor genes based on 5 annotations
Tgt molecule type
Interactor gene
Interactor species
Interactor molecule type
Detection methods
Source
Reference
protein
CG3434Drosophila melanogaster
protein
  • experimental knowledge based
PMID:22036573
protein
CG7737Drosophila melanogaster
protein
  • experimental knowledge based
PMID:22036573
protein
Hsp23Drosophila melanogaster
protein
  • experimental knowledge based
PMID:22036573
protein
Hsp26Drosophila melanogaster
protein
  • experimental knowledge based
PMID:22036573
protein
Hsp27Drosophila melanogaster
protein
  • experimental knowledge based
PMID:22036573
Showing 1 - 5 of 5 rows
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Genetic Interactions

No data available