Version: 8.0.0
Date: Tue Jan 28 2025
tou
Drosophila melanogasterFB:FBgn0033636
SummaryOrthologyParalogyFunction - GO AnnotationsPathwaysPhenotypesDisease AssociationsAlleles and VariantsTransgenic AllelesModelsSequence Feature ViewerSequence DetailsExpressionMolecular InteractionsGenetic Interactions
Gene

tou

Species
Drosophila melanogaster
Symbol
tou
Name
toutatis
Synonyms
  • anon-48Ad
  • CG10897
Biotype
protein coding gene
Automated Description
Enables DNA-binding transcription factor binding activity. Involved in chromatin remodeling; nervous system development; and positive regulation of transcription by RNA polymerase II. Part of ISWI-type complex. Colocalizes with polytene chromosome. Is expressed in several structures, including central brain primordium; ganglia; glial cell; gut section; and spermatozoon. Orthologous to human BAZ2A (bromodomain adjacent to zinc finger domain 2A) and BAZ2B (bromodomain adjacent to zinc finger domain 2B).
FB Description
toutatis (tou) encodes a transcription factor that activates proneural expression via positive regulation of the product of pnr. It is involved in chromatin remodeling and nervous system development.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR45915
No data available
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Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
Phenotype Term
Annotation details
References
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    Disease Associations

    Cases where the expected disease association was NOT found
    Cell color indicative of annotation volume
    Gene
    Association
    Disease Qualifier
    Disease
    Evidence
    Source
    Based On
    References
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      Alleles and Variants

      Allele/Variant Symbol
      Allele Synonyms
      Category
      Variant
      Variant type
      Molecular consequence
      Has Disease Annotations
      Has Phenotype Annotations
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        Transgenic Alleles

        Species
        (carrying the transgene)
        Allele symbol
        Transgenic construct
        Expressed components
        Knock-down targets
        Regulatory regions
        Has Disease Annotations
        Has Phenotype Annotations
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          Models

          Model name
          Experimental condition
          Associated Human Diseases
          Associated Phenotypes
          Modifier
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            Sequence Feature Viewer

            Genome location
            Assembly version
            R6
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            11.580M11.585M11.590M11.595M11.600M11.605M11.610M11.615M

            Sequence Details

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            Expression

            Primary Sources
            Other Sources
            Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

            Molecular Interactions

            tou molecule type
            Interactor gene
            Interactor species
            Interactor molecule type
            Detection methods
            Source
            Reference
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              Genetic Interactions

              tou role
              tou genetic perturbation
              Interactor gene
              Interactor species
              Interactor role
              Interactor genetic perturbation
              Interaction type
              Phenotype or trait
              Source
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