Version: 8.0.0
Date: Tue Jan 28 2025
γTub23C
Drosophila melanogasterFB:FBgn0260639
SummaryOrthologyParalogyFunction - GO AnnotationsPathwaysPhenotypesDisease AssociationsAlleles and VariantsTransgenic AllelesModelsSequence Feature ViewerSequence DetailsExpressionMolecular InteractionsGenetic Interactions
Gene

γTub23C

Species
Drosophila melanogaster
Symbol
γTub23C
Name
gamma-Tubulin at 23C
Synonyms
  • 23C gamma-tubulin
  • 23C-gamma-tubulin
Biotype
protein coding gene
Automated Description
Enables GTP binding activity. Contributes to microtubule minus-end binding activity. Involved in microtubule cytoskeleton organization; mitotic sister chromatid separation; and regulation of cell cycle. Located in cytoplasm and microtubule cytoskeleton. Part of gamma-tubulin ring complex and gamma-tubulin small complex. Is expressed in adult head and organism. Human ortholog(s) of this gene implicated in complex cortical dysplasia with other brain malformations 4; inclusion body myositis; and muscular disease. Orthologous to human TUBG1 (tubulin gamma 1).
FB Description
gamma-Tubulin at 23C (gammaTub23C) encodes the predominant member of the multi-protein gamma-tubulin ring complex (gammaTuRC), which templates the nucleation of microtubules.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR11588
No data available
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
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Annotation details
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    Disease Associations

    Cases where the expected disease association was NOT found
    Cell color indicative of annotation volume
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      Alleles and Variants

      Allele/Variant Symbol
      Allele Synonyms
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      Variant type
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        Transgenic Alleles

        Species
        (carrying the transgene)
        Allele symbol
        Transgenic construct
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        Regulatory regions
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          Models

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            Sequence Feature Viewer

            Genome location
            Assembly version
            R6
            Viewer Help
            2.9730M2.9732M2.9734M2.9736M2.9738M2.9740M2.9742M2.9744M2.9746M2.9748M

            Sequence Details

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            Expression

            Primary Sources
            Other Sources
            Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

            Molecular Interactions

            γTub23C molecule type
            Interactor gene
            Interactor species
            Interactor molecule type
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              Genetic Interactions

              γTub23C role
              γTub23C genetic perturbation
              Interactor gene
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