Gene

Trf2

Species
Drosophila melanogaster
Symbol
Trf2
Name
TATA box binding protein-related factor 2
Synonyms
  • CG11195
  • CG18009
Biotype
protein coding gene
Automated Description
Enables several functions, including RNA polymerase II core promoter sequence-specific DNA binding activity; TFIIA-class transcription factor complex binding activity; and chromatin binding activity. Contributes to RNA polymerase II general transcription initiation factor activity. Involved in several processes, including autophagic cell death; mRNA transcription by RNA polymerase II; and spiracle morphogenesis, open tracheal system. Located in chromosome and germ cell nucleus. Is expressed in several structures, including cyst cell of testis; germline cell; midline glial cell; midline primordium; and pole plasm. Orthologous to human TBPL1 (TATA-box binding protein like 1).
FB Description
TATA box binding protein-related factor 2 (Trf2) encodes a core promoter recognition factor that mediates gene transcription. It contributes to spiracle morphogenesis, pupal development and salivary gland cell death.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR10126
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R6
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8.410M8.412M8.414M8.416M8.418M8.420M8.422M8.424M8.426M8.428M8.430M8.432M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions