Predicted to enable calcium channel activity and calcium, potassium:sodium antiporter activity. Involved in calcium ion transmembrane transport and calcium-mediated signaling. Located in plasma membrane. Is expressed in several structures, including CNS glial cell; adult head; ganglia; larval nervous system; and ventral midline of embryo. Used to study epilepsy. Human ortholog(s) of this gene implicated in amelogenesis imperfecta hypomaturation type 2A5 and pigmentation disease. Orthologous to human SLC24A3 (solute carrier family 24 member 3) and SLC24A4 (solute carrier family 24 member 4).
FB Description
zydeco (zyd) encodes a potassium-dependent sodium/calcium exchanger found in cortex glia. It is thought to serve as a key calcium export pathway to control calcium oscillations that occur in membrane microdomains of the glial cell.