Gene

zyd

Species
Drosophila melanogaster
Symbol
zyd
Name
zydeco
Synonyms
  • BEST:CK02262
  • CG2893
Biotype
protein coding gene
Automated Description
Predicted to enable calcium channel activity and calcium, potassium:sodium antiporter activity. Involved in calcium ion transmembrane transport and calcium-mediated signaling. Located in plasma membrane. Is expressed in several structures, including CNS glial cell; adult head; ganglia; larval nervous system; and ventral midline of embryo. Used to study epilepsy. Human ortholog(s) of this gene implicated in amelogenesis imperfecta hypomaturation type 2A5 and pigmentation disease. Orthologous to human SLC24A3 (solute carrier family 24 member 3) and SLC24A4 (solute carrier family 24 member 4).
FB Description
zydeco (zyd) encodes a potassium-dependent sodium/calcium exchanger found in cortex glia. It is thought to serve as a key calcium export pathway to control calcium oscillations that occur in membrane microdomains of the glial cell.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR10846
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R6
Viewer Help
23.024M23.026M23.028M23.030M23.032M23.034M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions