Gene

Gyc76C

Species
Drosophila melanogaster
Symbol
Gyc76C
Name
Guanylyl cyclase at 76C
Synonyms
  • CG32215
  • CG42636
Biotype
protein coding gene
Automated Description
Enables guanylate cyclase activity; peptide receptor activity; and semaphorin receptor binding activity. Involved in several processes, including axon guidance; larval somatic muscle development; and primary branching, open tracheal system. Located in plasma membrane. Is expressed in several structures, including adult brain; adult digestive system; germline cell; gut section; and larval muscle cell.
FB Description
Guanylyl cyclase at 76C (Gyc76C) encodes a membrane-associated guanylate cyclase that catalyzes the conversion of GTP to the second messenger cGMP. It has roles in embryonic development (epithelia and muscle), axonal guidance, Malpighian tubule function, innate immunity and salt stress tolerance.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR11920
No data available
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Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None
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Annotation details
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    Disease Associations

    Cases where the expected disease association was NOT found
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      Alleles and Variants

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        Transgenic Alleles

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        (carrying the transgene)
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          Models

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            Sequence Feature Viewer

            Genome location
            Assembly version
            R6
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            19.755M19.760M19.765M19.770M19.775M19.780M19.785M19.790M

            Sequence Details

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            Expression

            Primary Sources
            Other Sources
            Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

            Molecular Interactions

            Gyc76C molecule type
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              Genetic Interactions

              Gyc76C role
              Gyc76C genetic perturbation
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