Gene

SNX16

Species
Homo sapiens
Symbol
SNX16
Name
sorting nexin 16
Synonyms
  • DKFZp666H147
  • sorting nexin-16
Biotype
protein coding gene
Automated Description
Enables identical protein binding activity and phosphatidylinositol binding activity. Involved in early endosome to late endosome transport; endosome to lysosome transport; and protein targeting to lysosome. Located in early endosome; endosome membrane; and late endosome.
RGD Description
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. The protein encoded by this gene associates with late endosome membranes as is involved in tubule formation, cholesterol transport, and transport of tetraspanin CD81. The encoded protein also inhibits cell migration and tumorigenesis. [provided by RefSeq, Jan 2017]
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR22999
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCh38
Viewer Help
81.800M81.805M81.810M81.815M81.820M81.825M81.830M81.835M81.840M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions