Gene

Bmp6

Species
Mus musculus
Symbol
Bmp6
Name
bone morphogenetic protein 6
Synonyms
  • D13Wsu115e
  • DNA segment, Chr 13, Wayne State University 115, expressed
Biotype
protein coding gene
Automated Description
Predicted to enable BMP receptor binding activity; protein heterodimerization activity; and receptor ligand activity. Involved in several processes, including multicellular organismal-level iron ion homeostasis; positive regulation of signal transduction; and regulation of transcription by RNA polymerase II. Acts upstream of or within several processes, including BMP signaling pathway; endochondral ossification; and male genitalia development. Located in extracellular space. Is expressed in several structures, including alimentary system; central nervous system; female reproductive system; skeleton; and visual system. Orthologous to human BMP6 (bone morphogenetic protein 6).
MGI Description
PHENOTYPE: One homozygous null mutant showed delayed ossification in the developing sternum while females of a second null mutant were smaller than normal in size. [provided by MGI curators]
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR11848
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCm39
Viewer Help
38.54M38.56M38.58M38.60M38.62M38.64M38.66M38.68M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions