Version: 8.0.0Date: Tue Jan 28 2025
Gene
Grik4
- Species
- Mus musculus
- Symbol
- Grik4
- Name
- glutamate receptor, ionotropic, kainate 4
- Synonyms
- 6330551K01Rik
- GluK4
- Biotype
- protein coding gene
- Automated Description
- Predicted to enable kainate selective glutamate receptor activity; ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential; and transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to be involved in glutamatergic synaptic transmission and modulation of chemical synaptic transmission. Located in membrane and synapse. Part of kainate selective glutamate receptor complex. Is active in hippocampal mossy fiber to CA3 synapse; postsynaptic membrane; and presynaptic membrane. Is expressed in brain; retina; and spinal cord. Orthologous to human GRIK4 (glutamate ionotropic receptor kainate type subunit 4).
- MGI Description
- PHENOTYPE: Mice homozygous for a knock-out allele exhibit reduced GYKI-resistant excitatory postsynaptic current. [provided by MGI curators]
- Cross References
- Additional Information
- Literature
Orthology
- Gene tree
- PANTHER:PTHR18966
Links to orthology data in JBrowse by filter level: Stringent, Moderate, No filter, Best and Best Reverse
Phenotypes
- Primary Sources
- Other Sources
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Disease Associations
Cases where the expected disease association was NOT found
Cell color indicative of annotation volume
No data available
Alleles and Variants
Allele/Variant Symbol | Allele Synonyms | Category | Variant | Variant type | Molecular consequence | Has Disease Annotations | Has Phenotype Annotations |
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Transgenic Alleles
Species (carrying the transgene) | Allele symbol | Transgenic construct | Expressed components | Knock-down targets | Regulatory regions | Has Disease Annotations | Has Phenotype Annotations |
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Models
Model name | Experimental condition | Associated Human Diseases | Associated Phenotypes | Modifier | Source |
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Sequence Feature Viewer
- Genome location
- Chr9:42431708...42856296 - (424.59 kb)
- Assembly version
- GRCm39
- Viewer Help
Data currently unavailable; sequence viewer under construction
Expression
- Primary Sources
- Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.