Enables pre-mRNA intronic binding activity. Involved in heart formation; negative regulation of mRNA splicing, via spliceosome; and regulation of alternative mRNA splicing, via spliceosome. Located in cytoplasmic ribonucleoprotein granule. Is active in nucleus. Human ortholog(s) of this gene implicated in dilated cardiomyopathy and dilated cardiomyopathy 1DD. Orthologous to human RBM20 (RNA binding motif protein 20).
RGD Description
Enables pre-mRNA intronic binding activity. Involved in heart formation; negative regulation of mRNA splicing, via spliceosome; and regulation of alternative mRNA splicing, via spliceosome. Located in cytoplasmic ribonucleoprotein granule. Is active in nucleus. Human ortholog(s) of this gene implicated in dilated cardiomyopathy and dilated cardiomyopathy 1DD. Orthologous to human RBM20 (RNA binding motif protein 20); INTERACTS WITH 1,3-dinitrobenzene; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol.