Gene

Tbx15

Species
Rattus norvegicus
Symbol
Tbx15
Name
T-box transcription factor 15
Synonyms
  • LOC295315
  • T-box 15
Biotype
protein coding gene
Automated Description
Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and protein homodimerization activity. Predicted to be involved in cell fate specification and negative regulation of transcription by RNA polymerase II. Predicted to act upstream of or within embryonic cranial skeleton morphogenesis. Predicted to be located in chromatin. Predicted to be part of RNA polymerase II transcription repressor complex. Predicted to be active in nucleus. Orthologous to human TBX15 (T-box transcription factor 15).
RGD Description
Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and protein homodimerization activity. Predicted to be involved in cell fate specification and negative regulation of transcription by RNA polymerase II. Predicted to act upstream of or within embryonic cranial skeleton morphogenesis. Predicted to be located in chromatin. Predicted to be part of RNA polymerase II transcription repressor complex. Predicted to be active in nucleus. Orthologous to human TBX15 (T-box transcription factor 15); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acrylamide; alpha-Zearalanol.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR11267
No data available
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None
Phenotype Term
Annotation details
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    Disease Associations

    Cases where the expected disease association was NOT found
    Cell color indicative of annotation volume
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      Alleles and Variants

      Allele/Variant Symbol
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      Variant
      Variant type
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        Transgenic Alleles

        Species
        (carrying the transgene)
        Allele symbol
        Transgenic construct
        Expressed components
        Knock-down targets
        Regulatory regions
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          Models

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            Sequence Feature Viewer

            Genome location
            Assembly version
            mRatBN7.2
            Viewer Help
            186.58M186.59M186.60M186.61M186.62M186.63M186.64M186.65M186.66M186.67M186.68M

            Sequence Details

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            Expression

            Primary Sources
            None
            Other Sources
            Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

            Molecular Interactions

            Tbx15 molecule type
            Interactor gene
            Interactor species
            Interactor molecule type
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              Genetic Interactions

              Tbx15 role
              Tbx15 genetic perturbation
              Interactor gene
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              Interactor role
              Interactor genetic perturbation
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