inhibitor of nuclear factor kappa B kinase subunit epsilon
Synonyms
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
inhibitor of kappaB kinase epsilon
Biotype
protein coding gene
Automated Description
Predicted to enable several functions, including IkappaB kinase activity; K48-linked polyubiquitin modification-dependent protein binding activity; and ubiquitin protein ligase binding activity. Predicted to be involved in several processes, including interleukin-17-mediated signaling pathway; positive regulation of gene expression; and positive regulation of innate immune response. Predicted to be located in PML body and mitochondrial membrane. Predicted to be active in cytoplasm. Orthologous to human IKBKE (inhibitor of nuclear factor kappa B kinase subunit epsilon).
RGD Description
Predicted to enable several functions, including IkappaB kinase activity; K48-linked polyubiquitin modification-dependent protein binding activity; and ubiquitin protein ligase binding activity. Predicted to be involved in several processes, including interleukin-17-mediated signaling pathway; positive regulation of innate immune response; and regulation of gene expression. Predicted to be located in PML body and mitochondrial membrane. Predicted to be active in cytoplasm. Orthologous to human IKBKE (inhibitor of nuclear factor kappa B kinase subunit epsilon); PARTICIPATES IN hepatitis C pathway; influenza A pathway; measles pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; acetamide.