SET domain bifurcated histone lysine methyltransferase 1
Synonyms
histone-lysine N-methyltransferase SETDB1
histone-lysine N-methyltransferase SETDB1-like
Biotype
protein coding gene
Automated Description
Predicted to enable DNA binding activity; histone H3K9 trimethyltransferase activity; and promoter-specific chromatin binding activity. Involved in response to ethanol and response to vitamin. Predicted to be located in cytoplasm and nucleoplasm. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in autistic disorder and lung cancer. Orthologous to human SETDB1 (SET domain bifurcated histone lysine methyltransferase 1).
RGD Description
Predicted to enable DNA binding activity; histone H3K9 trimethyltransferase activity; and promoter-specific chromatin binding activity. Involved in response to ethanol and response to vitamin. Predicted to be located in cytoplasm and nucleoplasm. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in autistic disorder and lung cancer. Orthologous to human SETDB1 (SET domain bifurcated histone lysine methyltransferase 1); PARTICIPATES IN histone modification pathway; homocysteine metabolic pathway; methionine cycle/metabolic pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; amitrole.