Gene

Guca1a

Species
Rattus norvegicus
Symbol
Guca1a
Name
guanylate cyclase activator 1A
Synonyms
  • guanylate cyclase activator 1a (retina)
  • guanylyl cyclase-activating protein 1
Biotype
protein coding gene
Automated Description
Predicted to enable calcium ion binding activity and calcium sensitive guanylate cyclase activator activity. Involved in positive regulation of cGMP-mediated signaling and positive regulation of guanylate cyclase activity. Located in photoreceptor inner segment and photoreceptor outer segment. Human ortholog(s) of this gene implicated in cone-rod dystrophy 14. Orthologous to human GUCA1A (guanylate cyclase activator 1A).
RGD Description
Predicted to enable calcium ion binding activity and calcium sensitive guanylate cyclase activator activity. Involved in positive regulation of cGMP-mediated signaling and positive regulation of guanylate cyclase activity. Located in photoreceptor inner segment and photoreceptor outer segment. Human ortholog(s) of this gene implicated in cone-rod dystrophy 14. Orthologous to human GUCA1A (guanylate cyclase activator 1A); PARTICIPATES IN calcium/calcium-mediated signaling pathway; visual phototransduction pathway; INTERACTS WITH amitrole; bisphenol A; clotrimazole.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR23055
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
13.589M13.590M13.591M13.592M13.593M13.594M13.595M13.596M13.597M13.598M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions