Predicted to enable actin binding activity and small GTPase binding activity. Predicted to be involved in several processes, including actin filament organization; barbed-end actin filament capping; and small GTPase-mediated signal transduction. Predicted to act upstream of or within several processes, including adult locomotory behavior; behavioral response to ethanol; and cellular response to leukemia inhibitory factor. Is active in glutamatergic synapse and postsynaptic density. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 102. Orthologous to human EPS8 (EGFR pathway substrate 8, signaling adaptor).
RGD Description
Predicted to enable actin binding activity and small GTPase binding activity. Predicted to be involved in several processes, including actin filament organization; barbed-end actin filament capping; and small GTPase-mediated signal transduction. Predicted to act upstream of or within several processes, including adult locomotory behavior; behavioral response to ethanol; and cellular response to leukemia inhibitory factor. Is active in glutamatergic synapse and postsynaptic density. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 102. Orthologous to human EPS8 (EGFR pathway substrate 8, signaling adaptor); PARTICIPATES IN platelet-derived growth factor signaling pathway; INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl.