Gene

Nlrp1a

Species
Rattus norvegicus
Symbol
Nlrp1a
Name
NLR family, pyrin domain containing 1A
Synonyms
  • LOC360557
  • NACHT, leucine rich repeat and PYD containing 1
Biotype
protein coding gene
Automated Description
Enables scaffold protein binding activity. Involved in negative regulation of cellular defense response and positive regulation of pyroptotic inflammatory response. Located in neuronal cell body. Part of protein-containing complex. Human ortholog(s) of this gene implicated in vitiligo. Orthologous to human NLRP1 (NLR family pyrin domain containing 1).
RGD Description
Enables scaffold protein binding activity. Involved in negative regulation of cellular defense response and positive regulation of pyroptotic inflammatory response. Located in neuronal cell body. Part of protein-containing complex. Human ortholog(s) of this gene implicated in vitiligo. Orthologous to human NLRP1 (NLR family pyrin domain containing 1); PARTICIPATES IN interleukin-1 signaling pathway; NOD-like receptor signaling pathway; INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR46985
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
55.780M55.785M55.790M55.795M55.800M55.805M55.810M55.815M55.820M55.825M55.830M

Sequence Details

Loading...

Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions