Gene

Gbp5

Species
Rattus norvegicus
Symbol
Gbp5
Name
guanylate binding protein 5
Synonyms
  • guanylate nucleotide binding protein 5
  • guanylate-binding protein 5
Biotype
protein coding gene
Automated Description
Predicted to enable several functions, including GTP binding activity; GTPase activity; and protein homodimerization activity. Predicted to be involved in several processes, including defense response to other organism; positive regulation of cytokine production; and positive regulation of defense response. Predicted to act upstream of or within response to bacterium. Predicted to be located in perinuclear region of cytoplasm. Predicted to be active in Golgi membrane; cytoplasmic vesicle; and symbiont cell surface. Orthologous to human GBP5 (guanylate binding protein 5).
RGD Description
Predicted to enable several functions, including GTP binding activity; GTPase activity; and protein homodimerization activity. Predicted to be involved in several processes, including defense response to other organism; positive regulation of cytokine production; and positive regulation of defense response. Predicted to act upstream of or within response to bacterium. Predicted to be located in perinuclear region of cytoplasm. Predicted to be active in Golgi membrane; cytoplasmic vesicle; and symbiont cell surface. Orthologous to human GBP5 (guanylate binding protein 5); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane; 6-propyl-2-thiouracil.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR10751
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None
No data available

Disease Associations

Cases where the expected disease association was NOT found
Must provide at least one subject
Cell color indicative of annotation volume

Transgenic Alleles

Models

No data available

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
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231.238M231.240M231.242M231.244M231.246M231.248M231.250M231.252M231.254M231.256M

Sequence Details

Transcript: Mode:

Expression

Primary Sources
None
Other Sources
Must provide at least one subject
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

No data available

Genetic Interactions