Enables hormone binding activity and melanocortin receptor activity. Involved in positive regulation of feeding behavior. Predicted to be active in cytoplasm and plasma membrane. Human ortholog(s) of this gene implicated in familial melanoma; major depressive disorder; melanoma; oculocutaneous albinism type II; and pigmentation disease. Orthologous to human MC1R (melanocortin 1 receptor).
RGD Description
Enables hormone binding activity and melanocortin receptor activity. Involved in positive regulation of feeding behavior. Predicted to be located in plasma membrane. Human ortholog(s) of this gene implicated in familial melanoma; major depressive disorder; melanoma; oculocutaneous albinism type II; and pigmentation disease. Orthologous to human MC1R (melanocortin 1 receptor); PARTICIPATES IN G protein mediated signaling pathway via Galphas family; melanocortin system pathway; INTERACTS WITH acrolein; thioacetamide; (-)-epigallocatechin 3-gallate (ortholog).