Version: 8.0.0
Date: Tue Jan 28 2025
Traf7
Rattus norvegicusRGD:1559653
SummaryOrthologyParalogyFunction - GO AnnotationsPathwaysPhenotypesDisease AssociationsAlleles and VariantsTransgenic AllelesModelsSequence Feature ViewerSequence DetailsExpressionMolecular InteractionsGenetic Interactions
Gene

Traf7

Species
Rattus norvegicus
Symbol
Traf7
Name
TNF receptor associated factor 7
Synonyms
  • E3 ubiquitin-protein ligase TRAF7
  • LOC360491
Biotype
protein coding gene
Automated Description
Predicted to enable ubiquitin protein ligase activity. Involved in positive regulation of neuron apoptotic process. Predicted to be located in several cellular components, including cytosol; perinuclear region of cytoplasm; and plasma membrane. Predicted to be part of ubiquitin ligase complex. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in adenomatoid tumor; hepatocellular carcinoma; and peritoneal mesothelioma. Orthologous to human TRAF7 (TNF receptor associated factor 7).
RGD Description
Predicted to enable ubiquitin protein ligase activity. Involved in positive regulation of neuron apoptotic process. Predicted to be located in several cellular components, including cytosol; perinuclear region of cytoplasm; and plasma membrane. Predicted to be part of ubiquitin ligase complex. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in adenomatoid tumor; hepatocellular carcinoma; and peritoneal mesothelioma. Orthologous to human TRAF7 (TNF receptor associated factor 7); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; ammonium chloride.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR19848
Stringency:
Additional filters to further constrain the results:
Species Gene symbol Count Best Best reverse
Method
Ensembl ComparaHGNCHieranoidInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidXenbaseZFIN
Homo sapiensTRAF710 of 10YesYes☑☑☑☑☑☑☑☑☑☑  
Mus musculusTraf79 of 9YesYes☑ ☑☑☑☑☑☑☑☑  
Xenopus tropicalistraf77 of 9YesYes☑ ☑☑☑☑☑☑☐☐  
Danio reriotraf78 of 9YesYes☑ ☑☑☑☑☑☐☑☑  
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Gene symbolRank Alignment Length (aa) Similarity %Identity %Method Count
Method
Ensembl ComparaHGNCInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidSGD
Btrc164439222 of 9☑☐☐☐☐☐☐☑☐ 
Fbxw7241946272 of 9☑☐☐☐☐☐☐☑☐ 
Nle1342039242 of 9☐☐☐☐☐☐☑☑☐ 
Fbxw11430848282 of 9☑☐☐☐☐☐☐☑☐ 
Wdr86529748282 of 9☑☐☐☐☐☐☐☑☐ 
Wdr95630939242 of 9☑☐☐☐☐☐☐☑☐ 

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None
No data available

Disease Associations

Cases where the expected disease association was NOT found
Must provide at least one subject
Cell color indicative of annotation volume
Species
Gene
Association
Disease Qualifier
Disease
Evidence
Source
Based On
References
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    Alleles and Variants

    Genome location
    Assembly version
    mRatBN7.2
    Viewer Help
    Data currently unavailable; sequence viewer under construction
    Allele/Variant Symbol
    Allele Synonyms
    Category
    Variant
    Variant type
    Molecular consequence
    Has Disease Annotations
    Has Phenotype Annotations
    NC_051345.1:g.13546476A>Tvariant
    SNP
    • intron variant
    NC_051345.1:g.13548717A>Gvariant
    SNP
    • intron variant
    NC_051345.1:g.13539188T>Cvariant
    SNP
    • intron variant
    NC_051345.1:g.13542583T>Cvariant
    SNP
    • intron variant
    NC_051345.1:g.13544909A>Gvariant
    SNP
    • intron variant
    NC_051345.1:g.13551282C>Tvariant
    SNP
    • intron variant
    NC_051345.1:g.13535475G>Tvariant
    SNP
    • intron variant
    NC_051345.1:g.13540883T>Cvariant
    SNP
    • intron variant
    NC_051345.1:g.13534236C>Gvariant
    SNP
    • intron variant
    NC_051345.1:g.13544085G>Avariant
    SNP
    • intron variant
    Showing 1 - 10 of 18 rows
    per page
    View detailed Alleles/Variants information
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    Transgenic Alleles

    No data available

    Models

    No data available

    Sequence Feature Viewer

    Genome location
    Assembly version
    mRatBN7.2
    Viewer Help
    Data currently unavailable; sequence viewer under construction

    Sequence Details

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    Expression

    Primary Sources
    None
    Other Sources
    Must provide at least one subject
    Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

    Molecular Interactions

    No data available

    Genetic Interactions

    No data available