Gene

Mir497

Species
Rattus norvegicus
Symbol
Mir497
Name
microRNA 497
Synonyms
  • microRNA mir-497
  • rno-mir-497
Biotype
ncRNA gene
Automated Description
Predicted to enable mRNA 3'-UTR binding activity and mRNA base-pairing translational repressor activity. Predicted to be involved in several processes, including miRNA-mediated gene silencing by mRNA destabilization; negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis; and negative regulation of signal transduction. Predicted to act upstream of or within response to bacterium; response to oxygen levels; and sensory perception of sound. Human ortholog(s) of this gene implicated in lung squamous cell carcinoma. Orthologous to human MIR497 (microRNA 497).
RGD Description
Predicted to enable mRNA 3'-UTR binding activity and mRNA base-pairing translational repressor activity. Predicted to be involved in several processes, including miRNA-mediated gene silencing by mRNA destabilization; negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis; and negative regulation of signal transduction. Predicted to act upstream of or within response to bacterium; response to oxygen levels; and sensory perception of sound. Human ortholog(s) of this gene implicated in lung squamous cell carcinoma. Orthologous to human MIR497 (microRNA 497); INTERACTS WITH 2,5-hexanedione; 3,7-dihydropurine-6-thione; aflatoxin B1.
Cross References
Additional Information
Literature

Orthology

Gene tree
Not Available
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
54.95151M54.95152M54.95153M54.95154M54.95155M54.95156M54.95157M54.95158M

Sequence Details

Loading...

Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions