Predicted to enable mRNA 3'-UTR binding activity and mRNA base-pairing translational repressor activity. Predicted to be involved in several processes, including miRNA-mediated gene silencing by mRNA destabilization; negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis; and negative regulation of signal transduction. Predicted to act upstream of or within response to bacterium; response to oxygen levels; and sensory perception of sound. Human ortholog(s) of this gene implicated in lung squamous cell carcinoma. Orthologous to human MIR497 (microRNA 497).
RGD Description
Predicted to enable mRNA 3'-UTR binding activity and mRNA base-pairing translational repressor activity. Predicted to be involved in several processes, including miRNA-mediated gene silencing by mRNA destabilization; negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis; and negative regulation of signal transduction. Predicted to act upstream of or within response to bacterium; response to oxygen levels; and sensory perception of sound. Human ortholog(s) of this gene implicated in lung squamous cell carcinoma. Orthologous to human MIR497 (microRNA 497); INTERACTS WITH 2,5-hexanedione; 3,7-dihydropurine-6-thione; aflatoxin B1.