Version: 8.0.0
Date: Tue Jan 28 2025
Chrng
Rattus norvegicusRGD:2354
SummaryOrthologyParalogyFunction - GO AnnotationsPathwaysPhenotypesDisease AssociationsAlleles and VariantsTransgenic AllelesModelsSequence Feature ViewerSequence DetailsExpressionMolecular InteractionsGenetic Interactions
Gene

Chrng

Species
Rattus norvegicus
Symbol
Chrng
Name
cholinergic receptor nicotinic gamma subunit
Synonyms
  • acetylcholine receptor subunit gamma
  • AChR gamma subunit
Biotype
protein coding gene
Automated Description
Enables acetylcholine-gated monoatomic cation-selective channel activity. Involved in monoatomic cation transport and skeletal muscle contraction. Part of acetylcholine-gated channel complex. Human ortholog(s) of this gene implicated in contractures, pterygia, and spondylocarpotarsal fusion syndrome. Orthologous to human CHRNG (cholinergic receptor nicotinic gamma subunit).
RGD Description
Enables acetylcholine-gated monoatomic cation-selective channel activity. Involved in monoatomic cation transport and skeletal muscle contraction. Part of acetylcholine-gated channel complex. Human ortholog(s) of this gene implicated in contractures, pterygia, and spondylocarpotarsal fusion syndrome. Orthologous to human CHRNG (cholinergic receptor nicotinic gamma subunit); PARTICIPATES IN acetylcholine signaling pathway via nicotinic acetylcholine receptor; INTERACTS WITH acetylcholine; acrylamide; ammonium chloride.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR11960
Stringency:
Additional filters to further constrain the results:
Species Gene symbol Count Best Best reverse
Method
Ensembl ComparaHGNCHieranoidInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidXenbaseZFIN
Homo sapiensCHRNG10 of 10YesYes☑☑☑☑☑☑☑☑☑☑  
Mus musculusChrng9 of 9YesYes☑ ☑☑☑☑☑☑☑☑  
Xenopus tropicalischrng3 of 9YesYes☐ ☐☐☐☑☐☑☑☐  
Danio reriochrng9 of 9YesYes☑ ☑☑☑☑☑☑☑☑  
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Gene symbolRank Alignment Length (aa) Similarity %Identity %Method Count
Method
Ensembl ComparaHGNCInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidSGD
Chrne149367522 of 9☐☐☐☐☐☐☑☑☐ 
Chrnd251962472 of 9☐☐☐☐☐☐☑☑☐ 
Chrnb1351760412 of 9☐☐☐☐☐☐☑☑☐ 
Chrna4464547332 of 9☐☐☐☐☐☐☑☑☐ 
Chrnb2549757412 of 9☐☐☐☐☐☐☑☑☐ 
Chrnb4652954362 of 9☐☐☐☐☐☐☑☑☐ 
Chrna2751154372 of 9☐☐☐☐☐☐☑☑☐ 
Chrna3853051332 of 9☐☐☐☐☐☐☑☑☐ 
Chrnb3951252312 of 9☐☐☐☐☐☐☑☑☐ 
Chrna51052950302 of 9☐☐☐☐☐☐☑☑☐ 
Chrna61151050322 of 9☐☐☐☐☐☐☑☑☐ 
Chrna11250551322 of 9☐☐☐☐☐☐☑☑☐ 
Chrna71354747302 of 9☐☐☐☐☐☐☑☑☐ 
Chrna101450846302 of 9☐☐☐☐☐☐☑☑☐ 
Chrna91547550312 of 9☐☐☐☐☐☐☑☑☐ 
Htr3a1654743262 of 9☐☐☐☐☐☐☑☑☐ 
Htr3b1742744242 of 9☐☐☐☐☐☐☑☑☐ 

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None
No data available

Disease Associations

Cases where the expected disease association was NOT found
Must provide at least one subject
Cell color indicative of annotation volume
Species
Gene
Association
Disease Qualifier
Disease
Evidence
Source
Based On
References
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    Alleles and Variants

    Genome location
    Assembly version
    mRatBN7.2
    Viewer Help
    Data currently unavailable; sequence viewer under construction
    Allele/Variant Symbol
    Allele Synonyms
    Category
    Variant
    Variant type
    Molecular consequence
    Has Disease Annotations
    Has Phenotype Annotations
    NC_051344.1:g.87878457G>Avariant
    SNP
    • missense variant
    NC_051344.1:g.87884048G>Avariant
    SNP
    • missense variant
    NC_051344.1:g.87878143G>Tvariant
    SNP
    • 5 prime UTR variant
    NC_051344.1:g.87879225G>Avariant
    SNP
    • intron variant
    NC_051344.1:g.87882003A>Cvariant
    SNP
    • intron variant
    NC_051344.1:g.87878974C>Tvariant
    SNP
    • intron variant
    NC_051344.1:g.87879012G>Cvariant
    SNP
    • intron variant
    NC_051344.1:g.87880908G>Avariant
    SNP
    • intron variant
    NC_051344.1:g.87881166G>Avariant
    SNP
    • intron variant
    NC_051344.1:g.87883398G>Avariant
    SNP
    • intron variant
    Showing 1 - 10 of 18 rows
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    Transgenic Alleles

    No data available

    Models

    No data available

    Sequence Feature Viewer

    Genome location
    Assembly version
    mRatBN7.2
    Viewer Help
    Data currently unavailable; sequence viewer under construction

    Sequence Details

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    Expression

    Primary Sources
    None
    Other Sources
    Must provide at least one subject
    Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

    Molecular Interactions

    No data available

    Genetic Interactions

    No data available