Enables sequence-specific DNA binding activity. Involved in several processes, including negative regulation of angiogenesis; negative regulation of transcription by RNA polymerase II; and negative regulation of vascular endothelial growth factor receptor signaling pathway. Predicted to be located in cytoplasm and nucleus. Predicted to be part of protein-DNA complex. Orthologous to human HHEX (hematopoietically expressed homeobox).
RGD Description
Enables sequence-specific DNA binding activity. Involved in several processes, including negative regulation of angiogenesis; negative regulation of transcription by RNA polymerase II; and negative regulation of vascular endothelial growth factor receptor signaling pathway. Predicted to be located in cytoplasm and nucleus. Predicted to be part of protein-DNA complex. Orthologous to human HHEX (hematopoietically expressed homeobox); PARTICIPATES IN maturity-onset diabetes of the young pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; ammonium chloride.