Species

Rattus norvegicus

Symbol

Zp2

Name

zona pellucida glycoprotein 2

Synonyms

zona pellucida 2 glycoprotein
zona pellucida glycoprotein 2 (sperm receptor)

Biotype

protein coding gene

Automated Description

Predicted to enable acrosin binding activity and identical protein binding activity. Predicted to be a structural constituent of egg coat. Predicted to be involved in binding activity of sperm to zona pellucida; humoral immune response mediated by circulating immunoglobulin; and prevention of polyspermy. Predicted to be located in several cellular components, including endoplasmic reticulum; inclusion body; and multivesicular body. Predicted to be active in collagen-containing extracellular matrix and egg coat. Orthologous to human ZP2 (zona pellucida glycoprotein 2).

RGD Description

Predicted to enable acrosin binding activity and identical protein binding activity. Predicted to be a structural constituent of egg coat. Predicted to be involved in binding activity of sperm to zona pellucida; humoral immune response mediated by circulating immunoglobulin; and prevention of polyspermy. Predicted to be located in several cellular components, including endoplasmic reticulum; inclusion body; and multivesicular body. Predicted to be active in collagen-containing extracellular matrix and egg coat. Orthologous to human ZP2 (zona pellucida glycoprotein 2); INTERACTS WITH 1,2-dimethylhydrazine; bis(2-ethylhexyl) phthalate; bisphenol A.

Cross References

Additional Information

Literature

Orthology

Gene tree: PANTHER:PTHR23343

No data available

Links to orthology data in JBrowse by filter level: Stringent, Moderate, No filter, Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources: None
Other Sources: None

Phenotype Term	Annotation details	References
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Disease Associations

Cell color indicative of annotation volume

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Alleles and Variants

Allele/Variant Symbol	Allele Synonyms	Category	Variant	Variant type	Molecular consequence	Has Disease Annotations	Has Phenotype Annotations
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Download all Alleles/Variants for all genes of the species

Transgenic Alleles

Species (carrying the transgene)	Allele symbol	Transgenic construct	Expressed components	Knock-down targets	Regulatory regions	Has Disease Annotations	Has Phenotype Annotations
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Models

Model name	Experimental condition	Associated Human Diseases	Associated Phenotypes	Modifier	Source
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Sequence Feature Viewer

Genome location

Chr1:174513507...174525288 - (11.78 kb)

Assembly version

mRatBN7.2

Viewer Help

Data currently unavailable; sequence viewer under construction

Sequence Details

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Expression

Primary Sources

None

Other Sources

Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Zp2 molecule type	Interactor gene	Interactor species	Interactor molecule type	Detection methods	Source	Reference
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Genetic Interactions

Zp2 role	Zp2 genetic perturbation	Interactor gene	Interactor species	Interactor role	Interactor genetic perturbation	Interaction type	Phenotype or trait	Source	Reference
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