Gene

eat-16

Species
Caenorhabditis elegans
Symbol
eat-16
Name
EATing: abnormal pharyngeal pumping 16
Synonyms
  • C16C2.2
  • CELE_C16C2.2
Biotype
protein coding gene
Automated Description
Enables GTPase activator activity. Involved in several processes, including G protein-coupled receptor signaling pathway; regulation of nematode pharyngeal pumping; and response to serotonin. Located in cytoplasm; neuron projection; and plasma membrane. Is expressed in neurons; pharyngeal muscle cell; and vulval muscle. Human ortholog(s) of this gene implicated in bradyopsia 1. Orthologous to human RGS9 (regulator of G protein signaling 9).
WB Description
The eat-16 gene encodes an RGS protein that affects movement, pharyngeal pumping, egg laying, and synaptic transmission; it genetically interacts with the egl-30 and goa-1 signaling pathways, and is expressed in excitable cells and in the spermatheca.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR45746
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
WBcel235
Viewer Help
9.7230M9.7235M9.7240M9.7245M9.7250M9.7255M9.7260M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions