NHL (ring finger b-box coiled coil) domain containing 1
Synonyms
CELE_F54G8.4
F54G8.4
Biotype
protein coding gene
Automated Description
Enables ubiquitin-protein transferase activity. Involved in protein ubiquitination. Is expressed in body wall musculature; non-striated muscle; pharynx; and reproductive system. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease type 2R. Orthologous to human TRIM2 (tripartite motif containing 2).
WB Description
The nhl-1 gene encodes an RBCC protein, orthologous to the mammalian protein BERP; its C. elegans paralogs include ncl-1 and lin-41.