Gene

rsp-2

Species
Caenorhabditis elegans
Symbol
rsp-2
Name
SR Protein (splicing factor) 2
Synonyms
  • CELE_W02B12.2
  • CeSRp40
Biotype
protein coding gene
Automated Description
Predicted to enable RNA binding activity. Involved in several processes, including gonad development; nematode larval development; and regulation of growth rate. Located in nucleus. Is expressed widely. Human ortholog(s) of this gene implicated in proliferative diabetic retinopathy and spermatogenic failure 3. Orthologous to human SRSF5 (serine and arginine rich splicing factor 5) and SRSF6 (serine and arginine rich splicing factor 6).
WB Description
rsp-2 encodes the C. elegans ortholog of the vertebrate SRp40 splicing factor and member of the SR protein family of nuclear phosphoproteins that are required for constitutive splicing and influence alternative splicing regulation.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR23147
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
WBcel235
Viewer Help
11.4516M11.4518M11.4520M11.4522M11.4524M11.4526M11.4528M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions