Predicted to enable RNA binding activity. Involved in several processes, including gonad development; nematode larval development; and regulation of growth rate. Located in nucleus. Is expressed widely. Human ortholog(s) of this gene implicated in proliferative diabetic retinopathy and spermatogenic failure 3. Orthologous to human SRSF5 (serine and arginine rich splicing factor 5) and SRSF6 (serine and arginine rich splicing factor 6).
WB Description
rsp-2 encodes the C. elegans ortholog of the vertebrate SRp40 splicing factor and member of the SR protein family of nuclear phosphoproteins that are required for constitutive splicing and influence alternative splicing regulation.