Gene

smc-3

Species
Caenorhabditis elegans
Symbol
smc-3
Name
SMC (structural maintenance of chromosomes) family 3
Synonyms
  • CELE_Y47D3A.26
  • Y47D3A
Biotype
protein coding gene
Automated Description
Predicted to enable double-stranded DNA binding activity. Predicted to be involved in mitotic sister chromatid cohesion. Located in chromatin. Part of cohesin complex. Human ortholog(s) of this gene implicated in Cornelia de Lange syndrome 3; hepatocellular carcinoma; and intellectual disability. Orthologous to human SMC3 (structural maintenance of chromosomes 3).
WB Description
Predicted to enable double-stranded DNA binding activity. Predicted to be involved in mitotic sister chromatid cohesion. Part of chromatin and cohesin complex. Human ortholog(s) of this gene implicated in Cornelia de Lange syndrome 3; hepatocellular carcinoma; and intellectual disability. Is an ortholog of human SMC3 (structural maintenance of chromosomes 3).
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR43977
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
WBcel235
Viewer Help
11.292M11.294M11.296M11.298M11.300M11.302M11.304M11.306M

Sequence Details

Loading...

Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions