Gene

twk-6

Species
Caenorhabditis elegans
Symbol
twk-6
Name
TWiK family of potassium channels 6
Synonyms
  • CELE_F17C8.5
  • F17C8.5
Biotype
protein coding gene
Automated Description
Predicted to enable outward rectifier potassium channel activity and potassium ion leak channel activity. Predicted to be involved in potassium ion transmembrane transport. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including gonadal sheath cell; intestine; nervous system; pharynx; and tail. Orthologous to several human genes including KCNK10 (potassium two pore domain channel subfamily K member 10); KCNK16 (potassium two pore domain channel subfamily K member 16); and KCNK17 (potassium two pore domain channel subfamily K member 17).
WB Description
twk-6 encodes one of 44 C. elegans TWK (two-P domain K+) potassium channel subunits that contain two pore-forming domains and four transmembrane domains; as loss of TWK-6 function via RNA-mediated interference (RNAi) does not result in any abnormalities, the precise role of TWK-6 in C. elegans development and/or behavior is not yet known; TWK-6 may, however, function redundantly with other TWK channels; TWK-6 is expressed in the hypodermis.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR11003
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
WBcel235
Viewer Help
4.7430M4.7432M4.7434M4.7436M4.7438M4.7440M4.7442M4.7444M4.7446M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions