Version: 8.0.0
Date: Tue Jan 28 2025
npr-16
Caenorhabditis elegansWB:WBGene00006864
SummaryOrthologyParalogyFunction - GO AnnotationsPathwaysPhenotypesDisease AssociationsAlleles and VariantsTransgenic AllelesModelsSequence Feature ViewerSequence DetailsExpressionMolecular InteractionsGenetic Interactions
Gene

npr-16

Species
Caenorhabditis elegans
Symbol
npr-16
Name
NeuroPeptide Receptor family 16
Synonyms
  • CELE_F56B6.5
  • F56B6.5
Biotype
protein coding gene
Automated Description
Predicted to enable G protein-coupled receptor activity and peptide binding activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Predicted to be active in neuron projection and plasma membrane. Is expressed in anal depressor muscle; neurons; ventral nerve cord; and vm1. Orthologous to human SSTR3 (somatostatin receptor 3).
WB Description
npr-16 encodes a G protein-coupled receptor that is most similar to the mammalian somatostatin receptors; npr-16 was first identified in molecular analyses of gene products linked to the vitellogenin (vit) loci on the X chromosome; npr-16 mRNA is expressed weakly in adult hermaphrodites.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR24229
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None
Phenotype Term
Annotation details
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    Disease Associations

    Cases where the expected disease association was NOT found
    Cell color indicative of annotation volume
    No data available

    Alleles and Variants

    Allele/Variant Symbol
    Allele Synonyms
    Category
    Variant
    Variant type
    Molecular consequence
    Has Disease Annotations
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      Transgenic Alleles

      Species
      (carrying the transgene)
      Allele symbol
      Transgenic construct
      Expressed components
      Knock-down targets
      Regulatory regions
      Has Disease Annotations
      Has Phenotype Annotations
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        Models

        Model name
        Experimental condition
        Associated Human Diseases
        Associated Phenotypes
        Modifier
        Source
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          Sequence Feature Viewer

          Genome location
          Assembly version
          WBcel235
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          Data currently unavailable; sequence viewer under construction

          Sequence Details

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          Expression

          Primary Sources
          Other Sources
          Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

          Molecular Interactions

          npr-16 molecule type
          Interactor gene
          Interactor species
          Interactor molecule type
          Detection methods
          Source
          Reference
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            Genetic Interactions

            npr-16 role
            npr-16 genetic perturbation
            Interactor gene
            Interactor species
            Interactor role
            Interactor genetic perturbation
            Interaction type
            Phenotype or trait
            Source
            Reference
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