Gene

set-6

Species
Caenorhabditis elegans
Symbol
set-6
Name
SET (trithorax/polycomb) domain containing 6
Synonyms
  • C49F5.2
  • CELE_C49F5.2
Biotype
protein coding gene
Automated Description
Enables histone H3K9 dimethyltransferase activity and histone H3K9 trimethyltransferase activity. Involved in epigenetic regulation of gene expression. Located in chromatin. Is expressed in embryonic cell; gonad; muscle cell; nervous system; and sperm. Orthologous to human SUV39H2 (SUV39H2 histone lysine methyltransferase).
WB Description
set-6 encodes a putative histone H3 lysine-9 methyltransferase; SET-6 has no non-nematode orthologs, but several paralogs (SET-13, SET-15, SET-19, SET-20, SET-21, and SET-32); neither set-6(tm1611) nor set-6(RNAi) have any obvious phenotypes.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR47250
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
WBcel235
Viewer Help
11.9705M11.9710M11.9715M11.9720M11.9725M11.9730M11.9735M11.9740M11.9745M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions