Enables histone H3K9 dimethyltransferase activity and histone H3K9 trimethyltransferase activity. Involved in epigenetic regulation of gene expression. Located in chromatin. Is expressed in embryonic cell; gonad; muscle cell; nervous system; and sperm. Orthologous to human SUV39H2 (SUV39H2 histone lysine methyltransferase).
WB Description
set-6 encodes a putative histone H3 lysine-9 methyltransferase; SET-6 has no non-nematode orthologs, but several paralogs (SET-13, SET-15, SET-19, SET-20, SET-21, and SET-32); neither set-6(tm1611) nor set-6(RNAi) have any obvious phenotypes.