Gene

mfb-1

Species
Caenorhabditis elegans
Symbol
mfb-1
Name
MAFBx (F-box) protein homolog 1
Synonyms
  • CELE_DY3.6
  • DY3.6
Biotype
protein coding gene
Automated Description
Predicted to be involved in protein ubiquitination. Predicted to be part of SCF ubiquitin ligase complex. Predicted to be active in cytoplasm and nucleus. Is expressed in several structures, including hypodermis; intestine; nervous system; reproductive system; and tail. Orthologous to human FBXO25 (F-box protein 25) and FBXO32 (F-box protein 32).
WB Description
Predicted to be involved in protein ubiquitination. Predicted to be located in cytoplasm and nucleus. Predicted to be part of SCF ubiquitin ligase complex. Expressed in several structures, including head; hypodermal cell; tail; touch receptor neurons; and ventral nerve cord. Human ortholog(s) of this gene implicated in primary pulmonary hypertension. Is an ortholog of human FBXO25 (F-box protein 25) and FBXO32 (F-box protein 32).
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR13123
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
WBcel235
Viewer Help
8.780M8.781M8.782M8.783M8.784M8.785M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions