Gene

myrf-2

Species
Caenorhabditis elegans
Symbol
myrf-2
Name
myelin regulatory factor related 2
Synonyms
  • CELE_F21A10.2
  • F21A10.2
Biotype
protein coding gene
Automated Description
Predicted to enable DNA-binding transcription factor activity and sequence-specific DNA binding activity. Predicted to be involved in positive regulation of DNA-templated transcription and protein autoprocessing. Predicted to be located in apical plasma membrane and endoplasmic reticulum. Predicted to be active in endoplasmic reticulum membrane and nucleus. Human ortholog(s) of this gene implicated in cerebral infarction; congenital diaphragmatic hernia; hyperopia; nanophthalmos; and primary angle-closure glaucoma. Orthologous to human MYRF (myelin regulatory factor) and MYRFL (myelin regulatory factor like).
WB Description
myrf-2 encodes a protein with a glutamine/asparagine-rich domain, homologous to human MYRF (myelin regulatory factor); MYRF-2 contains a well-conserved paralog in the C. elegans genome, MYRF-1, encoded by F59B10.1.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR13029
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
WBcel235
Viewer Help
10.182M10.184M10.186M10.188M10.190M10.192M10.194M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions