Gene

tatn-1

Species
Caenorhabditis elegans
Symbol
tatn-1
Name
Tyrosine AminoTraNsferase 1
Synonyms
  • CELE_F42D1.2
  • F42D1.2
Biotype
protein coding gene
Automated Description
Predicted to enable L-tyrosine-2-oxoglutarate transaminase activity. Involved in dauer entry. Is expressed in several structures, including body wall musculature; hypodermis; intestine; muscle cell; and pharynx. Human ortholog(s) of this gene implicated in tyrosinemia and tyrosinemia type II. Orthologous to human TAT (tyrosine aminotransferase).
WB Description
tatn-1 encodes a putative tyrosine aminotransferase, orthologous to human TAT (OMIM:276600, mutated in type II tyrosinemia); tatn-1 is expressed in larval and adult pharynx, hypodermis, body wall muscle, and intestine, and in adult vulval muscle and reproductive system; tatn-1 is required for the tyrosinemic phenotype of fah-1(RNAi) animals.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR45744
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
WBcel235
Viewer Help
14.7912M14.7914M14.7916M14.7918M14.7920M14.7922M14.7924M14.7926M14.7928M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions