Gene

vglu-2

Species
Caenorhabditis elegans
Symbol
vglu-2
Name
Vesicular GLUtamate transporter 2
Synonyms
  • CELE_K10G9.1
  • K10G9.1
Biotype
protein coding gene
Automated Description
Predicted to enable L-glutamate transmembrane transporter activity and neurotransmitter transmembrane transporter activity. Predicted to be involved in glutamatergic synaptic transmission; neurotransmitter loading into synaptic vesicle; and regulation of synapse structure or activity. Predicted to be located in membrane. Predicted to be active in excitatory synapse and synaptic vesicle membrane. Is expressed in AIA; hypodermis; uterine epithelial cell; and in male. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 25. Orthologous to human SLC17A6 (solute carrier family 17 member 6); SLC17A7 (solute carrier family 17 member 7); and SLC17A8 (solute carrier family 17 member 8).
WB Description
Predicted to enable L-glutamate transmembrane transporter activity and neurotransmitter transmembrane transporter activity. Predicted to be involved in several processes, including glutamatergic synaptic transmission; monoatomic anion transport; and neurotransmitter loading into synaptic vesicle. Predicted to be located in excitatory synapse and synaptic vesicle membrane. Expressed in AIAL; AIAR; hyp7 syncytium; uterine epithelial cell; and in male. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 25. Is an ortholog of human SLC17A6 (solute carrier family 17 member 6); SLC17A7 (solute carrier family 17 member 7); and SLC17A8 (solute carrier family 17 member 8).
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR11662
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
WBcel235
Viewer Help
10.2955M10.2960M10.2965M10.2970M10.2975M10.2980M10.2985M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions