Gene

B0432.7

Species
Caenorhabditis elegans
Symbol
B0432.7
Name
CIP2A N-terminal domain-containing protein
Synonyms
  • CELE_B0432.7
Biotype
protein coding gene
Automated Description
Orthologous to human CIP2A (cellular inhibitor of PP2A).
WB Description
Enriched in several structures, including ABaraapapaa; AFD; germ line; male distal tip cell; and pharyngeal cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including cyc-1; etr-1; and hsf-1 based on microarray and RNA-seq studies. Is affected by nine chemicals including rotenone; rifampin; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Protein CIP2A; Armadillo-type fold; CIP2A, N-terminal; and Phosphorylation site. Is an ortholog of human CIP2A (cellular inhibitor of PP2A). Human CIP2A enables protein homodimerization activity and protein phosphatase inhibitor activity.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR23161
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
WBcel235
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Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions