Predicted to enable RNA polymerase II complex binding activity. Involved in mRNA 3'-end processing. Is expressed in body wall musculature; nervous system; pharynx; and reproductive system. Orthologous to several human genes including RPRD1A (regulation of nuclear pre-mRNA domain containing 1A).
WB Description
cids-1 encodes a protein that contains a CTD (C-terminal domain of RNA Pol II)-interacting domain and that is orthologous to Saccharomyces cerevisiae RTT103; cids-1 was identified genetically as a suppressor of the SynMuv phenotype produced by lin-15AB(n765), a mutation that results in transposition of the 3'-end cleavage and polyadenylation signal of another gene into the third exon of lin-15B; qRT-PCR assays suggest that CIDS-1 plays a role in 3'-end cleavage.