Gene

cids-1

Species
Caenorhabditis elegans
Symbol
cids-1
Name
pol II C-terminal Interaction Domain Suppressor 1
Synonyms
  • C02F5.4
  • CELE_C02F5.4
Biotype
protein coding gene
Automated Description
Predicted to enable RNA polymerase II complex binding activity. Involved in mRNA 3'-end processing. Is expressed in body wall musculature; nervous system; pharynx; and reproductive system. Orthologous to several human genes including RPRD1A (regulation of nuclear pre-mRNA domain containing 1A).
WB Description
cids-1 encodes a protein that contains a CTD (C-terminal domain of RNA Pol II)-interacting domain and that is orthologous to Saccharomyces cerevisiae RTT103; cids-1 was identified genetically as a suppressor of the SynMuv phenotype produced by lin-15AB(n765), a mutation that results in transposition of the 3'-end cleavage and polyadenylation signal of another gene into the third exon of lin-15B; qRT-PCR assays suggest that CIDS-1 plays a role in 3'-end cleavage.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR12460
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
WBcel235
Viewer Help
8.2446M8.2448M8.2450M8.2452M8.2454M8.2456M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions