Predicted to enable inorganic anion transmembrane transporter activity and organic anion transmembrane transporter activity. Predicted to be involved in chloride transmembrane transport and sulfate transmembrane transport. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in body wall musculature; excretory cell; hypodermis; intestine; and neurons. Human ortholog(s) of this gene implicated in congenital secretory chloride diarrhea 1 and diarrhea. Orthologous to human SLC26A3 (solute carrier family 26 member 3).
WB Description
sulp-1 encodes one of eight C. elegans members of the sulfate permease family of anion transporters; by homology, SULP-1 is predicted to function as an anion transporter that regulates cellular pH and volume via transmembrane movement of electrolytes and fluids; a sulp-1::GFP transcriptional fusion is expressed strongly in several neurons, weakly in hypodermal cells and the intestine, and very faintly in the excretory cell and body wall muscle.