Gene

F10D7.5

Species
Caenorhabditis elegans
Symbol
F10D7.5
Name
Neuralized-like protein 2
Synonyms
  • CELE_F10D7.5
Biotype
protein coding gene
Automated Description
Predicted to enable ubiquitin protein ligase activity. Orthologous to several human genes including NEURL1 (neuralized E3 ubiquitin protein ligase 1) and NEURL1B (neuralized E3 ubiquitin protein ligase 1B).
WB Description
F10D7.5 encodes an ortholog of Drosophila NEURALIZED, and thus mayparticipate in GLP-1/LIN-12 signalling; the promoter or 5'protein-coding regions of F10D7.5 are bound by DAF-16 in vivo, andF10D7.5 expression drops by roughly one-half in daf-16(mu86) mutants.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR12429
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
WBcel235
Viewer Help
17.384M17.385M17.386M17.387M17.388M17.389M17.390M17.391M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions