Gene

ent-5

Species
Caenorhabditis elegans
Symbol
ent-5
Name
Equilibrative Nucleoside Transporter 5
Synonyms
  • CELE_F16H11.3
  • F16H11.3
Biotype
protein coding gene
Automated Description
Predicted to enable nucleoside transmembrane transporter activity. Predicted to be involved in nucleoside transmembrane transport. Predicted to be located in membrane. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in histiocytosis-lymphadenopathy plus syndrome. Orthologous to several human genes including SLC29A3 (solute carrier family 29 member 3).
WB Description
Predicted to enable nucleoside transmembrane transporter activity. Predicted to be involved in nucleoside transmembrane transport. Predicted to be located in plasma membrane. Human ortholog(s) of this gene implicated in histiocytosis-lymphadenopathy plus syndrome. Is an ortholog of human SLC29A3 (solute carrier family 29 member 3).
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR10332
Stringency:
Additional filters to further constrain the results:
Species Gene symbol Count Best Best reverse
Method
Ensembl ComparaHGNCHieranoidInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidXenbaseZFIN
Homo sapiensSLC29A36 of 9YesYes   
Homo sapiensSLC29A25 of 9NoYes   
Homo sapiensSLC29A14 of 9NoYes   
Mus musculusSlc29a36 of 9YesYes   
Mus musculusSlc29a15 of 9NoYes   
Mus musculusSlc29a24 of 9NoYes   
Rattus norvegicusSlc29a15 of 9YesYes   
Rattus norvegicusSlc29a25 of 9YesYes   
Rattus norvegicusSlc29a35 of 9YesYes   
Xenopus tropicalisslc29a22 of 9YesYes   
Danio rerioslc29a1b5 of 9YesYes   
Danio rerioslc29a25 of 9YesYes   
Danio rerioslc29a1a4 of 9NoYes   
Danio rerioslc29a33 of 9NoYes   
Drosophila melanogasterEnt24 of 9YesNo   
Saccharomyces cerevisiaeFUN263 of 9YesNo   
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Gene symbolRank Alignment Length (aa) Similarity %Identity %Method Count
Method
Ensembl ComparaHGNCInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidSGD
ent-4143161408 of 8  
ent-7241663417 of 8  
ent-1344156367 of 8  
ent-2443656367 of 8  
ent-3542155327 of 8  
ent-6645940225 of 8  

Function - GO Annotations

No function available for that gene

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None
No data available

Disease Associations

Cases where the expected disease association was NOT found
Must provide at least one subject
Cell color indicative of annotation volume
Species
Gene
Association
Disease Qualifier
Disease
Evidence
Source
Based On
References
Homo sapiensSLC29A3
is implicated inhistiocytosis-lymphadenopathy plus syndrome
  • IAGP
    Rattus norvegicusSlc29a1
    is implicated inbrain ischemia
    • IMP
      Mus musculusSlc29a1
      is implicated inalcohol dependence
      • TAS
        Mus musculusSlc29a1
        is implicated indiffuse idiopathic skeletal hyperostosis
        • TAS
          Showing 1 - 4 of 4 rows
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          Alleles and Variants

          Genome location
          Assembly version
          WBcel235
          Viewer Help
          4.6476M4.6478M4.6480M4.6482M4.6484M4.6486M4.6488M4.6490Ment-5F16H11.3.1
          Variant Types and ConsequencesOnly variants associated to alleles are shown in the graphics above. See all variants in JBrowse.
          Allele/Variant Symbol
          Allele Synonyms
          Category
          Variant
          Variant type
          Molecular consequence
          Has Disease Annotations
          Has Phenotype Annotations
          NC_003284.9:g.4647712G>Avariant
          SNP
          • missense variant
          NC_003284.9:g.4647820A>Gvariant
          SNP
          • synonymous variant
          NC_003284.9:g.4648092G>Avariant
          SNP
          • missense variant
          NC_003284.9:g.4648979G>Avariant
          SNP
          • missense variant
          NC_003284.9:g.4648779G>Avariant
          SNP
          • synonymous variant
          NC_003284.9:g.4648940C>Tvariant
          SNP
          • missense variant
          NC_003284.9:g.4647782G>Avariant
          SNP
          • missense variant
          NC_003284.9:g.4648701C>Tvariant
          NC_003284.9:g.4648455G>Avariant
          SNP
          • synonymous variant
          NC_003284.9:g.4647568C>Tvariant
          SNP
          • 3 prime UTR variant
          Showing 1 - 10 of 14 rows
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          Transgenic Alleles

          No data available

          Models

          No data available

          Sequence Feature Viewer

          Genome location
          Assembly version
          WBcel235
          Viewer Help
          4.6476M4.6478M4.6480M4.6482M4.6484M4.6486M4.6488M4.6490MF16H11.3.1 (ent-5)

          Sequence Details

          Transcript: Mode:
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          Expression

          Primary Sources
          Other Sources
          all annotationsall anatomical structuresalimentary part of gastrointestinal systemchemosensory systemcirculatory systemendocrine systemexocrine systemhemolymphoid systemhepatobiliary systemintegumental systemmechanosensory systemmusculoskeletal systemnervous systemrenal systemreproductive systemrespiratory systemsensory systemvestibulo-auditory systemvisual systemendodermectodermmesodermmesenchymeadipose tissueappendageentire extraembryonic componentimaginal precursorpharyngeal archotherall stagesembryo stagepost embryonic, pre-adultpost-juvenile adult stageall cellular componentsextracellular regionplasma membranesynapsecell junctioncell projectioncytoplasmic vesicleendosomevacuolegolgi apparatusendoplasmic reticulumcytosolmitochondrionnucleuschromosomecytoskeletonprotein-containing complexother locations
          Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

          Molecular Interactions

          4 interactor genes based on 4 annotations
          ent-5 molecule type
          Interactor gene
          Interactor species
          Interactor molecule type
          Detection methods
          Source
          Reference
          DNA
          cec-7Caenorhabditis elegans
          protein
          • one hybrid
          PMID:27777270
          DNA
          nhr-47Caenorhabditis elegans
          protein
          • one hybrid
          PMID:27777270
          DNA
          tbx-9Caenorhabditis elegans
          protein
          • one hybrid
          PMID:27777270
          DNA
          txt-18Caenorhabditis elegans
          protein
          • one hybrid
          PMID:27777270
          Showing 1 - 4 of 4 rows
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          Genetic Interactions

          No data available