Gene

svh-2

Species
Caenorhabditis elegans
Symbol
svh-2
Name
Suppressor of VHp-1 deletion lethality 2
Synonyms
  • CELE_T14E8.1
  • T14E8.1
Biotype
protein coding gene
Automated Description
Enables mitogen-activated protein kinase kinase kinase binding activity and transmembrane receptor protein tyrosine kinase activity. Involved in several processes, including axon regeneration; peptidyl-tyrosine autophosphorylation; and positive regulation of axon regeneration. Predicted to be part of receptor complex. Predicted to be active in plasma membrane. Is expressed in several structures, including distal tip cell; excretory cell; intestine; muscle cell; and pharynx. Orthologous to human TYRO3 (TYRO3 protein tyrosine kinase).
WB Description
Enables mitogen-activated protein kinase kinase kinase binding activity and transmembrane receptor protein tyrosine kinase activity. Involved in axon regeneration; positive regulation of MAPK cascade; and positive regulation of axon regeneration. Predicted to be located in plasma membrane. Predicted to be part of receptor complex. Expressed in distal tip cell; excretory canal; and muscle cell. Is an ortholog of human TYRO3 (TYRO3 protein tyrosine kinase).
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR24416
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
WBcel235
Viewer Help
6.554M6.555M6.556M6.557M6.558M6.559M6.560M6.561M6.562M6.563M6.564M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions