Gene

lron-8

Species
Caenorhabditis elegans
Symbol
lron-8
Name
eLRR (extracellular Leucine-Rich Repeat) ONly 8
Synonyms
  • CELE_T22E7.1
  • T22E7.1
Biotype
protein coding gene
Automated Description
Predicted to be located in membrane. Is expressed in body wall musculature; hypodermis; pharynx; and rectal gland cell. Human ortholog(s) of this gene implicated in autosomal recessive intellectual developmental disorder 64; congenital stationary night blindness 1A; glaucoma; and night blindness. Orthologous to several human genes including LINGO1 (leucine rich repeat and Ig domain containing 1); LINGO2 (leucine rich repeat and Ig domain containing 2); and LRRN1 (leucine rich repeat neuronal 1).
WB Description
Predicted to be located in extracellular matrix and extracellular space. Expressed in body wall musculature; head muscle; pharynx; and rectal gland cell. Human ortholog(s) of this gene implicated in several diseases, including autosomal recessive intellectual developmental disorder 64; congenital stationary night blindness 1A; and stomach cancer. Is an ortholog of several human genes including LRRN1 (leucine rich repeat neuronal 1); LRRN2 (leucine rich repeat neuronal 2); and LRRN3 (leucine rich repeat neuronal 3).
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR24373
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
WBcel235
Viewer Help
5.7690M5.7695M5.7700M5.7705M5.7710M5.7715M5.7720M5.7725M5.7730M5.7735M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions