Gene

hlcs

Species
Xenopus tropicalis
Symbol
hlcs
Name
holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
Synonyms
  • hlcs
  • holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
Biotype
gene
Automated Description
Predicted to enable biotin--[biotin carboxyl-carrier protein] ligase activity. Predicted to act upstream of or within protein modification process. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in holocarboxylase synthetase deficiency. Orthologous to human HLCS (holocarboxylase synthetase).
XBXT Description
Biotin holocarboxylase synthetase/biotin-protein ligase
https://www.xenbase.org/gene/showgene.do?method=display&geneId=1009303
Cross References
Additional Information
Literature

Orthology

Gene tree
Not Available
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
XT9.1
Viewer Help
8.64M8.65M8.66M8.67M8.68M8.69M8.70M8.71M8.72M

Sequence Details

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Expression

Primary Sources
Other Sources
None
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions