Predicted to be involved in mitochondrial DNA replication. Predicted to act upstream of or within DNA replication. Predicted to be active in mitochondrion. Human ortholog(s) of this gene implicated in autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions 4; mitochondrial DNA depletion syndrome 16; and mitochondrial DNA depletion syndrome 16B. Orthologous to human POLG2 (DNA polymerase gamma 2, accessory subunit).
XBXT Description
Glycyl-tRNA synthetase and related class II tRNA synthetase