SWI/SNF related BAF chromatin remodeling complex subunit ATPase 2
Synonyms
Brm
LOC432089
Biotype
gene
Automated Description
Predicted to enable DNA binding activity; chromatin binding activity; and nucleosome array spacer activity. Predicted to be involved in heterochromatin formation and positive regulation of transcription by RNA polymerase II. Predicted to act upstream of or within regulation of DNA-templated transcription. Predicted to be located in chromatin. Predicted to be part of SWI/SNF complex. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in Nicolaides-Baraitser syndrome and blepharophimosis-impaired intellectual development syndrome. Orthologous to human SMARCA2 (SWI/SNF related BAF chromatin remodeling complex subunit ATPase 2).
XBXT Description
Chromatin remodeling complex SWI/SNF, component SWI2 and related ATPases (DNA/RNA helicase superfamily)