Gene

snca

Species
Xenopus tropicalis
Symbol
snca
Name
synuclein alpha
Synonyms
  • alpha-snca
  • alpha-synuclein
Biotype
gene
Automated Description
Predicted to enable cuprous ion binding activity. Predicted to be involved in chemical synaptic transmission; synapse organization; and synaptic vesicle endocytosis. Predicted to act upstream of or within regulation of dopamine secretion. Predicted to be located in several cellular components, including extracellular region; nucleus; and synapse. Predicted to be active in axon terminus; cytoplasm; and neuronal cell body. Human ortholog(s) of this gene implicated in Alzheimer's disease; Lewy body dementia; Parkinson's disease; Parkinson's disease 1; and Parkinson's disease 4. Orthologous to several human genes including OTUD4 (OTU deubiquitinase 4).
XBXT Description
Cross References
Additional Information
Literature

Orthology

Gene tree
Not Available
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
XT9.1
Viewer Help
69.00M69.02M69.04M69.06M69.08M69.10M69.12M

Sequence Details

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Expression

Primary Sources
Other Sources
None
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions