Gene

npm1

Species
Xenopus tropicalis
Symbol
npm1
Name
nucleophosmin (nucleolar phosphoprotein B23, numatrin)
Synonyms
  • B23
  • npm
Biotype
gene
Automated Description
Predicted to enable RNA binding activity; chromatin binding activity; and histone binding activity. Predicted to be involved in several processes, including positive regulation of transcription by RNA polymerase II; regulation of centrosome duplication; and ribosome biogenesis. Predicted to be located in nucleus. Predicted to be part of ribonucleoprotein complex. Predicted to be active in centrosome; cytoplasm; and nuclear lumen. Is expressed in dermal system. Human ortholog(s) of this gene implicated in acute myeloid leukemia. Orthologous to human NPM1 (nucleophosmin 1).
XBXT Description
Cross References
Additional Information
Literature

Orthology

Gene tree
Not Available
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
XT9.1
Viewer Help
9.665M9.666M9.667M9.668M9.669M9.670M9.671M9.672M9.673M9.674M

Sequence Details

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Expression

Primary Sources
Other Sources
None
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions